Name : Frizzled 7 Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4421393133
| Long name | ALEXA FLUOR 555 Conjugated, Frizzled 7 Polyclonal Antibody |
| Also known as | Anti-Frizzled 7 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Frizzled 7 |
| Specificity | This is a highly specific antibody against Frizzled 7 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 550-574/574 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Frizzled 7 |
| Gene ID Number | 8324 |
| Swiss Prot | O75084 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes, which leads to the activation of disheveled proteins, Receptor for Wnt proteins |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | FzE3 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | Frizzled 7 |
| Short name | Frizzled 7 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, Frizzled 7 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4045 |
| Gene | FZD7 |
| Long gene name | frizzled class receptor 7 |
| Synonyms gene name | frizzled (Drosophila) homolog 7 frizzled homolog 7 (Drosophila) frizzled 7, seven transmembrane spanning receptor frizzled family receptor 7 |
| Locus | 2q33, 1 |
| Discovery year | 1998-09-17 |
| GenBank acession | AB010881 |
| Entrez gene record | 8324 |
| Pubmed identfication | 9707618 9813155 |
| RefSeq identity | NM_003507 |
| Classification | Class F frizzled , G protein-coupled receptors |
| Havana BLAST/BLAT | OTTHUMG00000132841 |