Name : Frizzled 9/CD349 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8232258439
| Long name | Frizzled 9/CD349 Primary Polyclonal Antibody |
| Also known as | Frizzled 9/CD349 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Frizzled 9/CD349 |
| Specificity | This antibody may have slight cross reactivity with Frizzled 10, This is a highly specific antibody against Frizzled 9/CD349 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 180-229/591 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Frizzled 9/CD349 |
| Gene ID number | 8326 |
| Swiss Prot | O00144 |
| Tested Applications | IF(IHC-P), IHC-P, FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), FCM(1:20-100) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes, which leads to the activation of disheveled proteins, Receptor for Wnt proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CD349, FZD9, Frizzled-9, Fz-9, FzE6, hFz9, FZD3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Frizzled 9/CD349 |
| Short name | Frizzled 9/CD349 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Frizzled 9/CD349 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4047 |
| Gene | FZD9 |
| Long gene name | frizzled class receptor 9 |
| Synonyms gene name | frizzled (Drosophila) homolog 9 frizzled homolog 9 (Drosophila) frizzled 9, seven transmembrane spanning receptor frizzled family receptor 9 |
| Synonyms | FZD3 CD349 |
| Locus | 7q11, 23 |
| Discovery year | 1998-09-17 |
| GenBank acession | U82169 |
| Entrez gene record | 8326 |
| Pubmed identfication | 9147651 10198163 |
| Classification | Class F frizzled CD molecules , G protein-coupled receptors |
| Havana BLAST/BLAT | OTTHUMG00000023051 |