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FTO Antibody

FTO Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFTO Primary Polyclonal Antibody
Also known asFTO PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFTO
SpecificityThis is a highly specific antibody against FTO
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range180-230/505
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fat mass and obesity-associated protein
Gene ID number79068
Swiss ProtQ9C0B1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Contributes to the regulation of body size and body fat accumulation, Contributes to the regulation of the global metabolic rate, Has highest activity towards single-stranded RNA containing 3-methyluracil, Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine, Has no activity towards 1-methylguanine, Has no detectable activity towards double-stranded DNA, Requires molecular oxygen, Specifically demethylates N(6)-methyladenosine (m6A) RNA, alpha-ketoglutarate and iron, energy expenditure and energy homeostasis, followed by single-stranded DNA containing 3-methylthymine, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes, Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Alpha-ketoglutarate-dependent dioxygenase FTO, FTO, Fat mass and obesity-associated protein, KIAA1752, ALKBH9
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFTO
Short nameFTO Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namefat mass and obesity associated (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-N1-methyladenine dioxygenase activity, FTO and IDBG-31147 and ENSG00000140718 and 79068, FTO and IDBG-631892 and ENSBTAG00000012501 and 618622, Fto and IDBG-179938 and ENSMUSG00000055932 and 26383, nuclei, this GO :0001659 and temperature homeostasis and biological process this GO :0005634 and nucleus and cellular component this GO :0006307 and DNA dealkylation involved in DNA repair and biological process this GO :0008198 and ferrous iron binding and molecular function this GO :0010883 and regulation of lipid storage and biological process this GO :0016607 and nuclear speck and cellular component this GO :0035515 and oxidative RNA demethylase activity and molecular function this GO :0035516 and oxidative DNA demethylase activity and molecular function this GO :0035552 and oxidative single-stranded DNA demethylation and biological process this GO :0035553 and oxidative single-stranded RNA demethylation and biological process this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0042245 and RNA repair and biological process this GO :0043734 and DNA-N1-methyladenine dioxygenase activity and molecular function this GO :0044065 and regulation of respiratory system process and biological process this GO :0060612 and adipose tissue development and biological process this GO :0070350 and regulation of white fat cell proliferation and biological process this GO :0070989 and oxidative demethylation and biological process this GO :0080111 and DNA demethylation and biological process, this GO :0008198: ferrous iron binding, this GO :0008198: ferrous iron binding and also this GO :0035515: oxidative RNA demethylase activity and also this GO :0035516: oxidative DNA demethylase activity and also this GO :0043734: DNA-N1-methyladenine dioxygenase activity, this GO :0035515: oxidative RNA demethylase activity, this GO :0035516: oxidative DNA demethylase activity, this GO :0043734: DNA-N1-methyladenine dioxygenase activity, fat mass and obesity associated
Identity 24678
Gene FTO
Long gene name FTO, alpha-ketoglutarate dependent dioxygenase
Synonyms gene name fat mass and obesity associated
Synonyms KIAA1752 MGC5149 ALKBH9
Synonyms name alkB homolog 9 alpha-ketoglutarate-dependent dioxygenase
Locus 16q12, 2
Discovery year 2007-04-12
GenBank acession BC003583
Entrez gene record 79068
Pubmed identfication 17434869 17991826 22002720
RefSeq identity NM_001080432
Classification Alkylation repair homologs
Havana BLAST/BLAT OTTHUMG00000158780

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