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Fukutin Antibody, ALEXA FLUOR 594

Fukutin Antibody, ALEXA FLUOR 594 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, Fukutin Polyclonal Antibody
Also known asAnti-Fukutin PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFukutin
SpecificityThis is a highly specific antibody against Fukutin
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fukutin
Gene ID Number282969
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen FCMD is the first human disease known to be caused by an ancient retrotransposal integration, Fukutin colocalizes with a Golgi marker and a granular cytoplasmic distribution, Fukutin deficiency affects the modification of glycosylation of DAG1 (Î, Fukutin may be located in the extracellular matrix, The fukutin gene is expressed at similar levels in control fetal and adult brain, The gene which encodes fukutin maps to human chromosome 9q31, a secreted protein, alternatively, as a secreted protein, but is much reduced in Fukuyama congenital muscular dystrophy (FCMD) brains, fukutin may cause muscular dystrophy by an unknown mechanism, is expressed in various tissues in normal individuals, suggesting that fukutin passes through the Golgi before being packaged into secretory vesicles, where it interacts with and reinforces a large complex encompassing the outside and inside of muscle membranes, which then cannot localize or function properly and may be degraded or eluted from the extracellular surface membrane of the muscle fiber, ±, -dystroglycan), Fukutin
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms LGMD2I MDC1C
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetFukutin
Short nameFukutin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, Fukutin (Antibody to)
Alternative techniqueantibodies
Identity 17997
Gene FKRP
Long gene name fukutin related protein
Locus 19q13, 32
Discovery year 2003-12-04
GenBank acession AJ314847
Entrez gene record 79147
Pubmed identfication 11592034 11741828
RefSeq identity NM_024301
Havana BLAST/BLAT OTTHUMG00000183177
Locus Specific Databases Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_761

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