Name : FXYD6 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6061091445
| Long name | Biotin Conjugated, FXYD6 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FXYD6 |
| Specificity | This is a highly specific antibody against FXYD6 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human FXYD6 |
| Gene ID number | 53826 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | After expression, FXYD2 (the g subunit of the Na+/K+-ATPase), FXYD3 (Mat8, FXYD4 (CHIF) and FXYD5 (RIC), FXYD6 associates with Na+/K+-ATPase alpha1-beta1 and alpha1-beta2 isozymes, FXYD6 co-localizes with Na+/K+-ATPase in the stria vascularis and can be co-immunoprecipitated with Na+/K+-ATPase, FXYD6 is expressed in various epithelial cells bordering the endolymph space and in the auditory neurons, FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, Members of the FXYD family include FXYD1 (PLM, beginning with the sequence PFXYD and containing seven invariant and six conserved amino acids, mammary tumor protein), muscle contraction and neuronal excitability, phospholemman), which are preferentially expressed in different regions of the inner ear and also with gastric and non-gastric H+/K+-ATPase, The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FXYD6 Conjugated |
| Short name | Conjugated, FXYD6 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, FXYD6 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4030 |
| Gene | FXYD6 |
| Long gene name | FXYD domain containing ion transport regulator 6 |
| Synonyms gene name | FXYD domain-containing ion transport regulator 6 |
| Synonyms name | phosphohippolin |
| Locus | 11q23, 3 |
| Discovery year | 2000-05-23 |
| GenBank acession | BC093040 |
| Entrez gene record | 53826 |
| Pubmed identfication | 10950925 |
| RefSeq identity | NM_022003 |
| Havana BLAST/BLAT | OTTHUMG00000166991 |