Name : Fyn Antibody
Supplier : NJS POLY
Price :199
SKU : GEN3750631212
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Fyn |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications | ELISA, WB |
| Recommended dilutions | Western blot: 1:1000 |
| Notes | Titration of the Fyn antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This Fyn antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P39688 |
| Purity | Antigen affinity |
| Description | Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC, Plays a role in the regulation of intracellular calcium levels, Required in brain development and mature brain function with important roles in the regulation of axon growth, and neurite extension, axon guidance, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1, Implicated in the control of cell growth |
| Immunogen | A portion of amino acids 507-535 from the mouse protein was used as the immunogen for this Fyn antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Fyn antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Fyn |
| Short name | Fyn Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | FGR, YES (Antibody to), FYN oncogene related to v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| Alternative technique | antibodies |
| Identity | 4037 |
| Gene | FYN |
| Long gene name | FYN proto-oncogene, Src family tyrosine kinase |
| Synonyms gene name | FGR, FYN oncogene related to SRC, YES |
| Synonyms | SYN SLK MGC45350 |
| Locus | 6q21 |
| Discovery year | 1988-08-19 |
| GenBank acession | AK056699 |
| Entrez gene record | 2534 |
| Pubmed identfication | 3526330 |
| Classification | SH2 domain containing Src family tyrosine kinases |
| Havana BLAST/BLAT | OTTHUMG00000016305 |