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FZD3/Frizzled 3 Antibody, ALEXA FLUOR 555

FZD3/Frizzled 3 Antibody, ALEXA FLUOR 555 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 555 Conjugated, FZD3/Frizzled 3 Polyclonal Antibody
Also known asAnti-FZD3/Frizzled 3 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFZD3/Frizzled 3
SpecificityThis is a highly specific antibody against FZD3/Frizzled 3
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range150-200/666
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FZD3/Frizzled 3
Gene ID Number7976
Swiss ProtQ9NPG1
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes, which leads to the activation of disheveled proteins, Receptor for Wnt proteins
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetFZD3/Frizzled 3
Short nameFZD3/Frizzled 3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, FZD3/Frizzled 3 (Antibody to)
Alternative techniqueantibodies
Identity 4041
Gene FZD3
Long gene name frizzled class receptor 3
Synonyms gene name frizzled (Drosophila) homolog 3 frizzled homolog 3 (Drosophila) frizzled 3, seven transmembrane spanning receptor frizzled family receptor 3
Locus 8p21, 1
Discovery year 1998-09-17
GenBank acession AJ272427
Entrez gene record 7976
Pubmed identfication 10777673 10873558
RefSeq identity NM_145866
Classification Class F frizzled , G protein-coupled receptors
Havana BLAST/BLAT OTTHUMG00000102145

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