FZR (1621CT637.76.67) Monoclonal Antibody

FZR (1621CT637.76.67) Monoclonal Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 281

Size 0.1ml

Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit

Long name	67) Monoclonal Antibody, 76, FZR (1621CT637
Also known as	67) Monoclonal Antibody, 76, FZR (1621CT637
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	FZR
Specificity	This is a highly specific antibody against FZR
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Monoclonal
Clone number	1621CT637, 67, 76
Source	This FZR antibody is generated from a mouse immunized with a recombinant protein between1-496 amino acids from human FZR
Gene ID number	51343
Swiss Prot	Q9UM11
Tested Applications	WB
Recommended dilutions	WB(1:2000)
Cross reactivity	Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Associates with the APC/C in late mitosis, At the G1/S transition FZR1 is phosphorylated, Following DNA damage, The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely, and activates the APC/C during anaphase and telophase, in replacement of CDC20, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, leading to its dissociation from the APC/C, preventing entry into mitosis, which confers substrate specificity upon the complex, Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C)
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	CDC20-like protein 1, CDC20C, CDH1, Cdh1/Hct1 homolog, FYR, FZR1, FZR2, Fizzy-related protein homolog, HCDH, HCDH1, KIAA1242, FZR
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About	Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target	67) Monoclonal, 76, FZR (1621CT637
Short name	67) Monoclonal Antibody, 76, FZR (1621CT637
Technique	Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name	67) monoclonal (Antibody to), 76, FZR (1621CT637
Alternative technique	antibodies
Identity	24824
Gene	FZR1
Long gene name	fizzy and cell division cycle 20 related 1
Synonyms gene name	fizzy/cell division cycle 20 related 1 (Drosophila) fizzy/cell division cycle 20 related 1
Synonyms	HCDH1 CDH1 HCDH FZR FZR2 KIAA1242 CDC20C
Synonyms name	CDC20 homolog 1
Locus	19p13, 3
Discovery year	2004-03-31
GenBank acession	AF083810
Entrez gene record	51343
Pubmed identfication	9734353 11003657
RefSeq identity	NM_016263
Classification	WD repeat domain containing
Havana BLAST/BLAT	OTTHUMG00000180747

FZR (1621CT637.76.67) Monoclonal Antibody

FZR (1621CT637.76.67) Monoclonal Antibody size: 0.1ml 281

Similar products

Subscribe to our Newsletter