Name : FZR1/CDC20C Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8222750777
| Long name | ALEXA FLUOR 555 Conjugated, FZR1/CDC20C Polyclonal Antibody |
| Also known as | Anti-FZR1/CDC20C PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FZR1/CDC20C |
| Specificity | This is a highly specific antibody against FZR1/CDC20C |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 150-200/496 |
| Subcellular location | Intracellular, Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FZR1/CDC20C |
| Gene ID Number | 51343 |
| Swiss Prot | Q9UM11 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Associates with the APC/C in late mitosis, At the G1/S transition FZR1 is phosphorylated, Following DNA damage, The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely, and activates the APC/C during anaphase and telophase, in replacement of CDC20, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, leading to its dissociation from the APC/C, preventing entry into mitosis, which confers substrate specificity upon the complex, Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | HCDH1 CDH1 HCDH FZR FZR2 KIAA1242 CDC20C |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | FZR1/CDC20C |
| Short name | FZR1/CDC20C Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, FZR1/CDC20C (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24824 |
| Gene | FZR1 |
| Long gene name | fizzy and cell division cycle 20 related 1 |
| Synonyms gene name | fizzy/cell division cycle 20 related 1 (Drosophila) fizzy/cell division cycle 20 related 1 |
| Synonyms name | CDC20 homolog 1 |
| Locus | 19p13, 3 |
| Discovery year | 2004-03-31 |
| GenBank acession | AF083810 |
| Entrez gene record | 51343 |
| Pubmed identfication | 9734353 11003657 |
| RefSeq identity | NM_016263 |
| Classification | WD repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000180747 |