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FZR1/CDC20C Antibody, Cy7 Conjugated

FZR1/CDC20C Antibody, Cy7 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy7 Conjugated, FZR1/CDC20C Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFZR1/CDC20C
SpecificityThis is a highly specific antibody against FZR1/CDC20C
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range150-200/496
Subcellular location Intracellular, Nucleus
SourceKLH conjugated synthetic peptide derived from human FZR1/CDC20C
Gene ID number51343
Swiss ProtQ9UM11
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Associates with the APC/C in late mitosis, At the G1/S transition FZR1 is phosphorylated, Following DNA damage, The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely, and activates the APC/C during anaphase and telophase, in replacement of CDC20, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, leading to its dissociation from the APC/C, preventing entry into mitosis, which confers substrate specificity upon the complex, Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms HCDH1 CDH1 HCDH FZR FZR2 KIAA1242 CDC20C
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetFZR1/CDC20C Conjugated
Short name Conjugated, FZR1/CDC20C Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, FZR1/CDC20C (Antibody to)
Alternative techniqueantibodies
Identity 24824
Gene FZR1
Long gene name fizzy and cell division cycle 20 related 1
Synonyms gene name fizzy/cell division cycle 20 related 1 (Drosophila) fizzy/cell division cycle 20 related 1
Synonyms name CDC20 homolog 1
Locus 19p13, 3
Discovery year 2004-03-31
GenBank acession AF083810
Entrez gene record 51343
Pubmed identfication 9734353 11003657
RefSeq identity NM_016263
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000180747

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