Name : FZR1/CDC20C Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN4142770917
| Long name | Cy7 Conjugated, FZR1/CDC20C Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FZR1/CDC20C |
| Specificity | This is a highly specific antibody against FZR1/CDC20C |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 150-200/496 |
| Subcellular location | Intracellular, Nucleus |
| Source | KLH conjugated synthetic peptide derived from human FZR1/CDC20C |
| Gene ID number | 51343 |
| Swiss Prot | Q9UM11 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Associates with the APC/C in late mitosis, At the G1/S transition FZR1 is phosphorylated, Following DNA damage, The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely, and activates the APC/C during anaphase and telophase, in replacement of CDC20, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, leading to its dissociation from the APC/C, preventing entry into mitosis, which confers substrate specificity upon the complex, Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | HCDH1 CDH1 HCDH FZR FZR2 KIAA1242 CDC20C |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | FZR1/CDC20C Conjugated |
| Short name | Conjugated, FZR1/CDC20C Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, FZR1/CDC20C (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24824 |
| Gene | FZR1 |
| Long gene name | fizzy and cell division cycle 20 related 1 |
| Synonyms gene name | fizzy/cell division cycle 20 related 1 (Drosophila) fizzy/cell division cycle 20 related 1 |
| Synonyms name | CDC20 homolog 1 |
| Locus | 19p13, 3 |
| Discovery year | 2004-03-31 |
| GenBank acession | AF083810 |
| Entrez gene record | 51343 |
| Pubmed identfication | 9734353 11003657 |
| RefSeq identity | NM_016263 |
| Classification | WD repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000180747 |