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G-CSF Antibody

G-CSF Antibody size: 0.1ml 354

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 354
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameG-CSF Primary Polyclonal Antibody
Also known asG-CSF PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenG-CSF
SpecificityThis is a highly specific antibody against G-CSF
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceRecombinant human protein purified from E, coli
Swiss ProtP09919
Tested Applications IP, WB
Recommended dilutions IP (5, 0ug), 5 ug/ml), WB (0
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Functionally, Human gene coding for G-CSF is assigned to the q21-q22 region of chromosome 17, The effect of G-CSF on myeloid leukemias is unique among colony stimulating factors in driving the leukemic cells from a self-renewing malignant state to a mature differentiated phenotype with the concomitant loss of tumorigenicity, The recombinant form of hG-CSF is capable of supporting neutrophil proliferation in a CFU-GM assay as well as early erythroid colonies and mixed colony formation, and a single gene of which codes for a 177 or 180 amino acid mature protein of molecular weight 19, and it almost exclusively stimulates the colony formation of granulocytes from committed precursor cells in semi-solid agar culture, consisting of 175 amino acids with the molecular mass of 18, it also prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes, it specifically stimulates the proliferation and differentiation of the progenitor cells for granulocytes, 1 G-CSF is also termed colony stimulating factor-3, 2 Besides, 3 The standard product used in this kit is recombinant human G-CSF, 600, 8KDa, Granulocyte colony-stimulating factor (G-CSF) is a member of the CSF family of hormone-like glycoprotein that regulates hematopoietic cell proliferation and differentiation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene CSF3
Gene targetG-CSF
Short nameG-CSF Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameG-CSF (Antibody to)
Alternative techniqueantibodies
Identity 2438
Long gene name colony stimulating factor 3
Synonyms gene GCSF G-CSF C17orf33
Synonyms gene name chromosome 17 open reading frame 33 colony stimulating factor 3 (granulocyte)
Synonyms MGC45931
Synonyms name granulocyte colony stimulating factor pluripoietin filgrastim lenograstim
Locus 17q21, 1
Discovery year 2001-06-22
Entrez gene record 1440
Pubmed identfication 3499671 3501046
RefSeq identity NM_172220
Classification Endogenous ligands
Havana BLAST/BLAT OTTHUMG00000133247

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