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G protein beta subunit like Antibody

G protein beta subunit like Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameG protein beta subunit like Antibody
Also known asG protein beta subunit like Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenG protein beta subunit like
SpecificityThis is a highly specific antibody against G protein beta subunit like
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human G protein beta subunit like
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis, Amino-acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases, Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, heart and kidney, mTORC1 is activated in response to growth factors or amino-acids, mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E), mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals, which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation, with highest levels in skeletal muscle, Subunit of both mTORC1 and mTORC2, Tissue specificity:Broadly expressed
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names G protein beta subunit-like, GBL, GBL protein, Gable, LST8_HUMAN, MGC111011, Mammalian lethal with SEC13 protein 8, Protein GbetaL, TORC subunit LST8, Target of rapamycin complex subunit LST8, mLST8, G protein beta subunit like
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetG protein beta subunit like
Short nameG protein beta subunit like Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameG protein b functionnal sequence like (Antibody to)
Alternative techniqueantibodies
Identity 4397
Gene GNB1L
Long gene name G protein subunit beta 1 like
Synonyms gene name beta polypeptide 1-like , guanine nucleotide binding protein (G protein)
Synonyms GY2 WDR14
Locus 22q11, 21
Discovery year 2000-06-16
GenBank acession AF238328
Entrez gene record 54584
Pubmed identfication 11072084
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000150279

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