GAB3 Antibody

GAB3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	GAB3 Primary Polyclonal Antibody
Also known as	GAB3 PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	GAB3
Specificity	This is a highly specific antibody against GAB3
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GAB3
Gene ID number	139716
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Cytokine/growth factor triggering of protein tyrosine kinase receptors (RTKs) initiates signaling cascades that progress to the nucleus where signals for activation, Gab1-3 contain pleckstrin homology and potential binding sites for SH2 and SH3 domain-containing proteins (1, Insulin receptor and EGF-receptor signaling are among the cascades that rely on Gab family members to elicit a nuclear response to an extracellular stimulus (6, The human Gab3 gene maps to chromosome Xq28 and encodes a 586 amino acid protein (5), The recruitment of signaling partners to Gab family members is phosphorylation dependent (1, This scaffolding mechanism represents a critical link in cytokine/growth factor signaling routes, proliferation and differentiation occur (1â, &euro, &euro, &ldquo, &ldquo, 3), 3), 4, 4), 5), 7), The Gab family of adaptor proteins function as molecular scaffolds that mediate protein recrutiment to RTKs (1â
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	GAB3_HUMAN, GRB2-associated binder 3, GRB2-associated-binding protein 3, Growth factor receptor bound protein 2-associated protein 3, Gab3
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	GAB3
Short name	GAB3 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	GAB3 (Antibody to)
Alternative technique	antibodies
Identity	17515
Gene	GAB3
Long gene name	GRB2 associated binding protein 3
Synonyms name	DOS/Gab family member 3 Gab3 scaffolding protein
Locus	Xq28
Discovery year	2002-03-05
GenBank acession	AY057989
Entrez gene record	139716
Pubmed identfication	11739737
RefSeq identity	NM_001081573
Classification	Pleckstrin homology domain containing
Havana BLAST/BLAT	OTTHUMG00000024245
Locus Specific Databases	Mental Retardation database

GAB3 Antibody

GAB3 Antibody size: 0.1ml 263

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