Filters

GAB4 Antibody, Biotin Conjugated

GAB4 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, GAB4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGAB4
SpecificityThis is a highly specific antibody against GAB4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GAB4
Gene ID number128954
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Cytokine/growth factor triggering of protein tyrosine kinase receptors (RTKs) initiates signaling cascades that progress to the nucleus where signals for activation, Gab 1-4 contain Pleckstrin homology and potential binding sites for SH2 and SH3 domain-containing proteins, Gab 4 (GRB2-associated-binding protein 4), Insulin receptor and EGF receptor signaling are among the cascades that rely on Gab family members to elicit a nuclear response to an extracellular stimulus, The recruitment of signaling partners to Gab family members is phosphorylation-dependent, This scaffolding mechanism represents a critical link in cytokine/growth factor signaling routes, also designated GRB2-associated-binding protein 2-like (Gab 2-like), is a 574 amino acid protein that shares 62% sequence similarity with Gab 2 and contains one Pleckstrin homology domain, proliferation and differentiation occur, The Gab family of adaptor proteins function as molecular scaffolds that mediate protein recruit-ment to RTKs
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGAB4 Conjugated
Short name Conjugated, GAB4 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, member 4 (Antibody to), GRB2-associated binding protein family
Alternative techniqueantibodies
Alternative to gene target GAB2 and IDBG-642116 and ENSBTAG00000002922 and 529346, GAB4 and IDBG-227875 and ENSG00000215568 and 128954, Gab2 and IDBG-199566 and ENSMUSG00000004508 and 14389, member 4, multiple, GRB2-associated binding protein family
Identity 18325
Gene GAB4
Long gene name GRB2 associated binding protein family member 4
Synonyms gene name GRB2-associated binding protein family, member 4
Locus 22q11, 1
Discovery year 2004-07-22
GenBank acession AK057252
Entrez gene record 128954
RefSeq identity XM_372882
Classification Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000149992

Similar products

Subscribe to our Newsletter