Name : GABBR2 (Ser783) Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN3418245856
| Long name | Cy3 Conjugated, GABBR2 (Ser783) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GABBR2 Ser783 |
| Specificity | This is a highly specific antibody against GABBR2 Ser783 |
| Modification | Phosphorylation |
| Modification site | Ser783 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human GABBR2 around the phosphorylation site of Ser783 |
| Gene ID number | 9568 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, Plays a critical role in the fine-tuning of inhibitory synaptic transmission, Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis, muscle relaxation and antinociception, slow wave sleep, stimulates phospholipase A2, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials, Receptor for GABA |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | HG20 GABABR2 GPRC3B |
| Properties | 1 of the GABBR2 (Ser783) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GABBR2 (Ser783) Conjugated |
| Short name | Conjugated, GABBR2 (Ser783) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, GABBR2 (Ser783) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4507 |
| Gene | GABBR2 |
| Long gene name | gamma-aminobutyric acid type B receptor subunit 2 |
| Synonyms gene | GPR51 |
| Synonyms gene name | 2 , G protein-coupled receptor 51 gamma-aminobutyric acid (GABA) B receptor |
| Locus | 9q22, 33 |
| Discovery year | 1999-04-23 |
| GenBank acession | AF069755 |
| Entrez gene record | 9568 |
| Pubmed identfication | 10087195 |
| Classification | Gamma-aminobutyric acid type B receptor subunits |
| Havana BLAST/BLAT | OTTHUMG00000020345 |