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GABBR2 (Ser783) Antibody, FITC Conjugated

GABBR2 (Ser783) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, GABBR2 (Ser783) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGABBR2 Ser783
SpecificityThis is a highly specific antibody against GABBR2 Ser783
ModificationPhosphorylation
Modification siteSer783
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human GABBR2 around the phosphorylation site of Ser783
Gene ID number9568
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, Plays a critical role in the fine-tuning of inhibitory synaptic transmission, Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis, muscle relaxation and antinociception, slow wave sleep, stimulates phospholipase A2, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials, Receptor for GABA
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms HG20 GABABR2 GPRC3B
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGABBR2 (Ser783) Conjugated
Short name FITC Conjugated, GABBR2 (Ser783) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, GABBR2 (Ser783) (Antibody to)
Alternative techniqueantibodies
Identity 4507
Gene GABBR2
Long gene name gamma-aminobutyric acid type B receptor subunit 2
Synonyms gene GPR51
Synonyms gene name 2 , G protein-coupled receptor 51 gamma-aminobutyric acid (GABA) B receptor
Locus 9q22, 33
Discovery year 1999-04-23
GenBank acession AF069755
Entrez gene record 9568
Pubmed identfication 10087195
Classification Gamma-aminobutyric acid type B receptor subunits
Havana BLAST/BLAT OTTHUMG00000020345

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