Name : GABPA/NRF2A Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN4473613631
| Long name | Cy7 Conjugated, GABPA/NRF2A Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GABPA/NRF2A |
| Specificity | This is a highly specific antibody against GABPA/NRF2A |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human GABPA/NRF2A |
| Gene ID number | 2551 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini, GABP beta, GABP beta is expressed in both the cytoplasm and the nucleus, GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, In primary neuronal cultures, The GABP alpha beta tetrameric complex performs many different functions, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription, both of which can modify GABP-dependent transcription in vitro and in vivo, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, such as stimulating transcription of the adenovirus E4 gene, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, whereas GABP alpha is expressed mainly in the nucleus, The transcription factor GA-binding protein (GABP) is composed of two subunits |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | E4TF1A NFT2 NRF2 E4TF1-60 NRF2A |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | GABPA/NRF2A Conjugated |
| Short name | Conjugated, GABPA/NRF2A Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, GABPA/NRF2A (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4071 |
| Gene | GABPA |
| Long gene name | GA binding protein transcription factor alpha subunit |
| Synonyms gene name | GA-binding protein transcription factor, alpha subunit (60kD) GA binding protein transcription factor, alpha subunit 60kDa |
| Synonyms name | human nuclear respiratory factor-2 subunit alpha nuclear respiratory factor 2 alpha subunit |
| Locus | 21q21, 3 |
| Discovery year | 1994-01-18 |
| Entrez gene record | 2551 |
| Pubmed identfication | 8441384 |
| RefSeq identity | NM_002040 |
| Classification | ETS transcription factor family |
| Havana BLAST/BLAT | OTTHUMG00000078443 |