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GABPA/NRF2A Antibody, FITC Conjugated

GABPA/NRF2A Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, GABPA/NRF2A Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGABPA/NRF2A
SpecificityThis is a highly specific antibody against GABPA/NRF2A
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GABPA/NRF2A
Gene ID number2551
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background GABP alpha binds to a specific DNA sequence and GABP beta exists as b1 and b2 splice variants that differ in their C-termini, GABP beta, GABP beta is expressed in both the cytoplasm and the nucleus, GABP is constitutively expressed as either a GABP alpha beta heterodimer or a GABP alpha b heterotetramer, In primary neuronal cultures, The GABP alpha beta tetrameric complex performs many different functions, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription, both of which can modify GABP-dependent transcription in vitro and in vivo, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, such as stimulating transcription of the adenovirus E4 gene, the Ets-related GABP-alpha and a GABP-alpha-associated subunit, whereas GABP alpha is expressed mainly in the nucleus, The transcription factor GA-binding protein (GABP) is composed of two subunits
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms E4TF1A NFT2 NRF2 E4TF1-60 NRF2A
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGABPA/NRF2A Conjugated
Short name FITC Conjugated, GABPA/NRF2A Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, GABPA/NRF2A (Antibody to)
Alternative techniqueantibodies
Identity 4071
Gene GABPA
Long gene name GA binding protein transcription factor alpha subunit
Synonyms gene name GA-binding protein transcription factor, alpha subunit (60kD) GA binding protein transcription factor, alpha subunit 60kDa
Synonyms name human nuclear respiratory factor-2 subunit alpha nuclear respiratory factor 2 alpha subunit
Locus 21q21, 3
Discovery year 1994-01-18
Entrez gene record 2551
Pubmed identfication 8441384
RefSeq identity NM_002040
Classification ETS transcription factor family
Havana BLAST/BLAT OTTHUMG00000078443

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