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GABRG2(Ser366) Antibody

GABRG2(Ser366) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGABRG2(Ser366) Primary Polyclonal Antibody
Also known asGABRG2(Ser366) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGABRG2 Ser366
SpecificityThis is a highly specific antibody against GABRG2 Ser366
Modification(s)Phosphorylation
Modification site(s)Ser366
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human GABRG2 around the phosphorylation site of Ser366
Gene ID number2566
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Beta, Defects in the gene encoding GABAA R Gamma 2 have been found to be the cause of childhood absence epilepsy type 2, Delta and Epsilon), GABA functions as the main inhibitory transmitter by increasing a Cl- (chloride) conductance that inhibits neuronal firing, GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors, GABAA R? is a 467 amino acid mulit-pass membrane protein localized to the postsynaptic cell membrane, Gamma, In the central nervous system, Present as a pentamer with other GABAA receptor chains (Alpha, The ?subunit of GABAA receptors are important for benzodiazepine binding and modulation of GABA-mediated Cl- current, as well as a third class of receptors called GABAC, familial febrile convulsions type 8, function to catalyze the production of GABA (gamma-aminobutyric acid), generalized epilepsy with febrile seizures plus type 3 and severe myoclonic epilepsy in infancy, glutamate decarboxylases, the GABAA ligand-gated Cl- channels selectively complex with D5DR to enable mutual inhibitory functional interactions between the two receptor systems, GAD-65 and GAD-67
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CAE 2, CAE2, ECA 2, ECA2, GABAA receptor subunit gamma 2, GABAA receptor subunit gamma-2, GABRG 2, GABRG2 antibody Gamma aminobutyric acid GABA A receptor gamma 2, GBRG2_HUMAN, GEFSP 3, GEFSP3, Gamma aminobutyric acid A receptor gamma 2, Gamma aminobutyric acid receptor gamma 2 subunit, Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric-acid receptor gamma-2 subunit, ³, 2 Ser 365, p-GABAA RÎ
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGABRG2(Ser366)
Short nameGABRG2(Ser366) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGABRG2(Ser366) (Antibody to)
Alternative techniqueantibodies
Identity 4087
Gene GABRG2
Long gene name gamma-aminobutyric acid type A receptor gamma2 subunit
Synonyms gene name gamma 2 , gamma-aminobutyric acid (GABA) A receptor
Synonyms name GABA(A) receptor, gamma 2
Locus 5q34
Discovery year 1991-02-26
Classification Gamma-aminobutyric acid type A receptor subunits
Havana BLAST/BLAT OTTHUMG00000130350

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