Name : GADD34 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2661476513
| Long name | GADD34 Primary Polyclonal Antibody |
| Also known as | GADD34 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GADD34 |
| Specificity | This is a highly specific antibody against GADD34 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 415-450/674 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GADD34 |
| Gene ID number | 23645 |
| Swiss Prot | O75807 |
| Tested Applications | IF(IHC-P), IHC-P, FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), FCM(1:20-100) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1, May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15', thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress, Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Growth arrest and DNA damage-inducible protein GADD34, Myeloid differentiation primary response protein MyD116 homolog, PPP1R15A, Protein phosphatase 1 regulatory subunit 15A, GADD34 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GADD34 |
| Short name | GADD34 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GADD34 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 14375 |
| Gene | PPP1R15A |
| Long gene name | protein phosphatase 1 regulatory subunit 15A |
| Synonyms gene name | protein phosphatase 1, regulatory (inhibitor) subunit 15A protein phosphatase 1, regulatory subunit 15A |
| Synonyms | GADD34 |
| Synonyms name | growth arrest and DNA-damage-inducible 34 |
| Locus | 19q13, 2 |
| Discovery year | 2001-06-29 |
| GenBank acession | U83981 |
| Entrez gene record | 23645 |
| Pubmed identfication | 9153226 9413226 |
| RefSeq identity | NM_014330 |
| Classification | Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT | OTTHUMG00000183330 |