Name : GADD34 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3807679728
| Long name | ALEXA FLUOR 647 Conjugated, GADD34 Polyclonal Antibody |
| Also known as | Anti-GADD34 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GADD34 |
| Specificity | This is a highly specific antibody against GADD34 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 415-450/674 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GADD34 |
| Gene ID Number | 23645 |
| Swiss Prot | O75807 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1, May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15', thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress, Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | GADD34 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the GADD34 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | GADD34 |
| Short name | GADD34 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, GADD34 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 14375 |
| Gene | PPP1R15A |
| Long gene name | protein phosphatase 1 regulatory subunit 15A |
| Synonyms gene name | protein phosphatase 1, regulatory (inhibitor) subunit 15A protein phosphatase 1, regulatory subunit 15A |
| Synonyms name | growth arrest and DNA-damage-inducible 34 |
| Locus | 19q13, 2 |
| Discovery year | 2001-06-29 |
| GenBank acession | U83981 |
| Entrez gene record | 23645 |
| Pubmed identfication | 9153226 9413226 |
| RefSeq identity | NM_014330 |
| Classification | Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT | OTTHUMG00000183330 |