Filters

GADD34 Antibody, FITC Conjugated

GADD34 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, GADD34 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGADD34
SpecificityThis is a highly specific antibody against GADD34
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range415-450/674
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human GADD34
Gene ID number23645
Swiss ProtO75807
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1, May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15', thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress, Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms GADD34
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGADD34 Conjugated
Short name FITC Conjugated, GADD34 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, GADD34 (Antibody to)
Alternative techniqueantibodies
Identity 14375
Gene PPP1R15A
Long gene name protein phosphatase 1 regulatory subunit 15A
Synonyms gene name protein phosphatase 1, regulatory (inhibitor) subunit 15A protein phosphatase 1, regulatory subunit 15A
Synonyms name growth arrest and DNA-damage-inducible 34
Locus 19q13, 2
Discovery year 2001-06-29
GenBank acession U83981
Entrez gene record 23645
Pubmed identfication 9153226 9413226
RefSeq identity NM_014330
Classification Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000183330

Subscribe to our Newsletter