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GADD45A Antibody

GADD45A Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenGADD45A
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the GADD45A antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis GADD45A antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P24522
PurityAntigen affinity
Description GADD45A promotes epigenetic gene activation by repair-mediated DNA demethylation, Northern blot analysis detected moderate expression of a 1, Papathanasiou et al, Sequence analysis of human and hamster cDNA clones demonstrated that the gene has been highly conserved and encodes a novel 165-amino acid polypeptide, This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents, and kidney, and pancreas, liver, lung, placenta, skeletal muscle, with little or no expression in brain, (1991) demonstrated that the gene is located on 1p34-p12, 4-kb GADD45A transcript in heart, Growth arrest and DNA-damage-inducible protein is a protein that in humans is encoded by the GADD45A gene
Immunogen mouse and rat), An amino acid sequence from the C-terminus of human GADD45A (NPHSSQWKDPALSQL) was used as the immunogen for this GADD45A antibody (100% homologous in human
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the GADD45A antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetGADD45A
Short nameGADD45A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name a (Antibody to), growth arrest and Desoxyribonucleic acid-damage-inducible
Alternative techniqueantibodies
Alternative to gene target DDIT1 and GADD45, GADD45A and IDBG-638096 and ENSBTAG00000013860 and 505463, GADD45A and IDBG-99580 and ENSG00000116717 and 1647, Gadd45a and IDBG-153723 and ENSMUSG00000036390 and 13197, alpha, nuclei, protein binding, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000185 and activation of MAPKKK activity and biological process this GO :0001047 and core promoter binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006281 and DNA repair and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006915 and apoptotic process and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007098 and centrosome cycle and biological process this GO :0042770 and signal transduction in response to DNA damage and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071479 and cellular response to ionizing radiation and biological process this GO :1900745 and positive regulation of p38MAPK cascade and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process, this GO :0001047: core promoter binding, this GO :0001047: core promoter binding and also this GO :0005515: protein binding, this GO :0005515: protein binding, growth arrest and DNA-damage-inducible
Identity 4095
Gene GADD45A
Long gene name growth arrest and DNA damage inducible alpha
Synonyms gene DDIT1
Synonyms gene name alpha , growth arrest and DNA-damage-inducible
Synonyms GADD45
Locus 1p31, 3
Discovery year 1991-08-17
GenBank acession M60974
Entrez gene record 1647
Pubmed identfication 1990262 8226988
RefSeq identity NM_001924
Havana BLAST/BLAT OTTHUMG00000009374

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