Name : GADL1 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3944982519
| Long name | ALEXA FLUOR 594 Conjugated, GADL1 Polyclonal Antibody |
| Also known as | Anti-GADL1 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GADL1 |
| Specificity | This is a highly specific antibody against GADL1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GADL1 |
| Gene ID Number | 339896 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Although both GADs are found in brain, As a member of the group II decarboxylase family, GAD or SCP), GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, GAD-65 transiently activates to assist in GABA production, GAD-67 is responsible for the basal levels of GABA synthesis, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity, In the case of a heightened demand for GABA in neurotransmission, There are two isoforms of GADL1 that exist as a result of alternative splicing events, while GAD-67 is distributed throughout the cell, There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | GADL1 |
| Short name | GADL1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, GADL1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 27949 |
| Gene | GADL1 |
| Long gene name | glutamate decarboxylase like 1 |
| Synonyms gene name | glutamate decarboxylase-like 1 |
| Locus | 3p24, 1-p23 |
| Discovery year | 2004-07-28 |
| GenBank acession | AK128643 |
| Entrez gene record | 339896 |
| RefSeq identity | NM_207359 |
| Havana BLAST/BLAT | OTTHUMG00000130621 |