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GADL1 Antibody, Biotin Conjugated

GADL1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, GADL1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGADL1
SpecificityThis is a highly specific antibody against GADL1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GADL1
Gene ID number339896
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Although both GADs are found in brain, As a member of the group II decarboxylase family, GAD or SCP), GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, GAD-65 transiently activates to assist in GABA production, GAD-67 is responsible for the basal levels of GABA synthesis, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity, In the case of a heightened demand for GABA in neurotransmission, There are two isoforms of GADL1 that exist as a result of alternative splicing events, while GAD-67 is distributed throughout the cell, There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGADL1 Conjugated
Short name Conjugated, GADL1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, GADL1 (Antibody to)
Alternative techniqueantibodies
Identity 27949
Gene GADL1
Long gene name glutamate decarboxylase like 1
Synonyms gene name glutamate decarboxylase-like 1
Locus 3p24, 1-p23
Discovery year 2004-07-28
GenBank acession AK128643
Entrez gene record 339896
RefSeq identity NM_207359
Havana BLAST/BLAT OTTHUMG00000130621

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