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GAMT Antibody

GAMT Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGAMT Primary Polyclonal Antibody
Also known asGAMT PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGAMT
SpecificityThis is a highly specific antibody against GAMT
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range150-200/236
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GAMT
Gene ID number2593
Swiss ProtQ14353
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in the GAMT gene leads to GAMT deficiency, Encoding a 236 amino acid protein, GAMT, Methyltransferases are a type of transferase enzyme which transfers a methyl group to nucleic bases in DNA or amino acids in protein, Such biochemical changes are thought to lead to various neurological syndromes and muscular hypotonia, a methyltransferase, and guanidinoacetate is then converted to creatine by Guanidinoacetate N-methyltransferase (GAMT), glycine is converted to guanidinoacetate by amidinotransferase, the human GAMT gene maps to chromosome 19p13, uses S-adenosylmethionine as the methyl donor for this reaction, which is associated with guanidinoacetate accumulation and decreased levels of creatine excretion in brain, 3, In the creatine biosynthesis pathway
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CCDS2, GAMT, Guanidinoacetate N-methyltransferase, HEL-S-20, TP53I2, PIG2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGAMT
Short nameGAMT Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGAMT (Antibody to)
Alternative techniqueantibodies
Identity 4136
Gene GAMT
Long gene name guanidinoacetate N-methyltransferase
Synonyms PIG2 TP53I2
Locus 19p13, 3
Discovery year 1996-07-19
GenBank acession Z49878
Entrez gene record 2593
Pubmed identfication 9570966 8547310
RefSeq identity NM_138924
Havana BLAST/BLAT OTTHUMG00000180095
Locus Specific Databases LOVD - Leiden Open Variation Database

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