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GAPDH (1A10A10) Monoclonal Antibody

GAPDH (1A10A10) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGAPDH (1A10A10) Monoclonal Antibody
Also known asGAPDH (1A10A10) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGAPDH
SpecificityThis is a highly specific antibody against GAPDH
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1A10A10
SourceGAPDH recombinant protein is used to produce this monoclonal antibody
Gene ID number2597
Swiss ProtP04406
Tested Applications IF, IHC-P, WB
Recommended dilutions IHC-P(1:25), WB(1:1000-5000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes, DNA replication and apoptosis, Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity), Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate, HDAC2 and PRKDC, Modulates the organization and assembly of the cytoskeleton, Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, Participates in nuclear events including transcription, RNA transport, Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation, respectively, thereby playing a role in glycolysis and nuclear functions, Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities
Purification method This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CDABP0047, GAPD, GAPDH, Glyceraldehyde-3-phosphate dehydrogenase, HEL-S-162eP, OK/SW-cl, Peptidyl-cysteine S-nitrosylase GAPDH, 12, G3PD
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetGAPDH (1A10A10) Monoclonal
Short nameGAPDH (1A10A10) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative nameGAPDH (1A10A10) monoclonal (Antibody to)
Alternative techniqueantibodies
Identity 4141
Gene GAPDH
Long gene name glyceraldehyde-3-phosphate dehydrogenase
Synonyms gene GAPD
Locus 12p13, 31
Discovery year 2001-06-22
GenBank acession AF261085
Entrez gene record 2597
Pubmed identfication 3170585
RefSeq identity NM_002046
Havana BLAST/BLAT OTTHUMG00000137379

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