Name : GAPDH Antibody, Cy5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN5290007685
| Long name | Cy5 Conjugated, GAPDH Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GAPDH |
| Specificity | This is a highly specific antibody against GAPDH |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Cytoplasm |
| Source | GAPDH protein of rabbit |
| Gene ID number | 2597 |
| Swiss Prot | P04406 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes, DNA replication and apoptosis, Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity), Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate, HDAC2 and PRKDC, Modulates the organization and assembly of the cytoskeleton, Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, Participates in nuclear events including transcription, RNA transport, Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation, respectively, thereby playing a role in glycolysis and nuclear functions, Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 625, 650nm/670nm |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GAPDH Conjugated |
| Short name | Conjugated, GAPDH Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy5 |
| Alternative name | cyanine 5 coupled, GAPDH (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4141 |
| Gene | GAPDH |
| Long gene name | glyceraldehyde-3-phosphate dehydrogenase |
| Synonyms gene | GAPD |
| Locus | 12p13, 31 |
| Discovery year | 2001-06-22 |
| GenBank acession | AF261085 |
| Entrez gene record | 2597 |
| Pubmed identfication | 3170585 |
| RefSeq identity | NM_002046 |
| Havana BLAST/BLAT | OTTHUMG00000137379 |