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GARNL1 Antibody

GARNL1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGARNL1 Primary Polyclonal Antibody
Also known asGARNL1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGARNL1
SpecificityThis is a highly specific antibody against GARNL1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GARNL1
Gene ID number253959
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen During development, GARNL1 activity does not involve E12 and therefore it may serve a different function in developed neural tissue, GARNL1 expression decreases, GARNL1 interacts with the HLH region of E12 and may function to negatively regulate the transcription of E12-dependent downstream target genes, GARNL1 is imported to the nucleus via dimerization with E12, GARNL1 localizes to the cytoplasm where it may play a role regulating GTP hydrolysis of proteins such as Ran and Rap, GARNL1 may also associate with other HLH proteins and influence a variety of HLH signaling cascades, In adult brain, This suggests that at least a portion of the function of GARNL1 is dependent upon its association with E12, persisting at high levels only in neurons of the adult brain, GARNL1 is expressed during embryogenesis with E12
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DKFZp667F074, GAP related interacting partner to E12, GARN L1, GARNL 1, GRIPE, GTPase activating Rap/RanGAP domain like 1, KIAA0884, RGPA1_HUMAN, TULIP 1, TULIP1, Tuberin like protein 1, DKFZp566D133
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGARNL1
Short nameGARNL1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGARNL1 (Antibody to)
Alternative techniqueantibodies
Identity 17770
Gene RALGAPA1
Long gene name Ral GTPase activating protein catalytic alpha subunit 1
Synonyms gene GARNL1
Synonyms gene name GTPase activating RANGAP domain-like 1 GTPase activating Rap/RanGAP domain-like 1
Synonyms GRIPE DKFZp667F074 KIAA0884 Tulip1 RalGAPalpha1
Synonyms name tuberin-like protein 1 GAP-related interacting protein to E12
Locus 14q13, 2
Discovery year 2003-10-09
GenBank acession AK126975
Entrez gene record 253959
Pubmed identfication 19520869
RefSeq identity XM_210022
Havana BLAST/BLAT OTTHUMG00000170619

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