Name : GARNL1 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9347612971
| Long name | ALEXA FLUOR 488 Conjugated, GARNL1 Polyclonal Antibody |
| Also known as | Anti-GARNL1 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GARNL1 |
| Specificity | This is a highly specific antibody against GARNL1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GARNL1 |
| Gene ID Number | 253959 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | During development, GARNL1 activity does not involve E12 and therefore it may serve a different function in developed neural tissue, GARNL1 expression decreases, GARNL1 interacts with the HLH region of E12 and may function to negatively regulate the transcription of E12-dependent downstream target genes, GARNL1 is imported to the nucleus via dimerization with E12, GARNL1 localizes to the cytoplasm where it may play a role regulating GTP hydrolysis of proteins such as Ran and Rap, GARNL1 may also associate with other HLH proteins and influence a variety of HLH signaling cascades, In adult brain, This suggests that at least a portion of the function of GARNL1 is dependent upon its association with E12, persisting at high levels only in neurons of the adult brain, GARNL1 is expressed during embryogenesis with E12 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | GRIPE DKFZp667F074 KIAA0884 Tulip1 RalGAPalpha1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the GARNL1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | GARNL1 |
| Short name | GARNL1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, GARNL1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17770 |
| Gene | RALGAPA1 |
| Long gene name | Ral GTPase activating protein catalytic alpha subunit 1 |
| Synonyms gene | GARNL1 |
| Synonyms gene name | GTPase activating RANGAP domain-like 1 GTPase activating Rap/RanGAP domain-like 1 |
| Synonyms name | tuberin-like protein 1 GAP-related interacting protein to E12 |
| Locus | 14q13, 2 |
| Discovery year | 2003-10-09 |
| GenBank acession | AK126975 |
| Entrez gene record | 253959 |
| Pubmed identfication | 19520869 |
| RefSeq identity | XM_210022 |
| Havana BLAST/BLAT | OTTHUMG00000170619 |