Name : GARNL1 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN9687726090
| Long name | Cy3 Conjugated, GARNL1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GARNL1 |
| Specificity | This is a highly specific antibody against GARNL1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human GARNL1 |
| Gene ID number | 253959 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | During development, GARNL1 activity does not involve E12 and therefore it may serve a different function in developed neural tissue, GARNL1 expression decreases, GARNL1 interacts with the HLH region of E12 and may function to negatively regulate the transcription of E12-dependent downstream target genes, GARNL1 is imported to the nucleus via dimerization with E12, GARNL1 localizes to the cytoplasm where it may play a role regulating GTP hydrolysis of proteins such as Ran and Rap, GARNL1 may also associate with other HLH proteins and influence a variety of HLH signaling cascades, In adult brain, This suggests that at least a portion of the function of GARNL1 is dependent upon its association with E12, persisting at high levels only in neurons of the adult brain, GARNL1 is expressed during embryogenesis with E12 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | GRIPE DKFZp667F074 KIAA0884 Tulip1 RalGAPalpha1 |
| Properties | 1 of the GARNL1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GARNL1 Conjugated |
| Short name | Conjugated, GARNL1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, GARNL1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17770 |
| Gene | RALGAPA1 |
| Long gene name | Ral GTPase activating protein catalytic alpha subunit 1 |
| Synonyms gene | GARNL1 |
| Synonyms gene name | GTPase activating RANGAP domain-like 1 GTPase activating Rap/RanGAP domain-like 1 |
| Synonyms name | tuberin-like protein 1 GAP-related interacting protein to E12 |
| Locus | 14q13, 2 |
| Discovery year | 2003-10-09 |
| GenBank acession | AK126975 |
| Entrez gene record | 253959 |
| Pubmed identfication | 19520869 |
| RefSeq identity | XM_210022 |
| Havana BLAST/BLAT | OTTHUMG00000170619 |