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GARNL1 Antibody, Cy7 Conjugated

GARNL1 Antibody, Cy7 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy7 Conjugated, GARNL1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGARNL1
SpecificityThis is a highly specific antibody against GARNL1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GARNL1
Gene ID number253959
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background During development, GARNL1 activity does not involve E12 and therefore it may serve a different function in developed neural tissue, GARNL1 expression decreases, GARNL1 interacts with the HLH region of E12 and may function to negatively regulate the transcription of E12-dependent downstream target genes, GARNL1 is imported to the nucleus via dimerization with E12, GARNL1 localizes to the cytoplasm where it may play a role regulating GTP hydrolysis of proteins such as Ran and Rap, GARNL1 may also associate with other HLH proteins and influence a variety of HLH signaling cascades, In adult brain, This suggests that at least a portion of the function of GARNL1 is dependent upon its association with E12, persisting at high levels only in neurons of the adult brain, GARNL1 is expressed during embryogenesis with E12
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms GRIPE DKFZp667F074 KIAA0884 Tulip1 RalGAPalpha1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetGARNL1 Conjugated
Short name Conjugated, GARNL1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, GARNL1 (Antibody to)
Alternative techniqueantibodies
Identity 17770
Gene RALGAPA1
Long gene name Ral GTPase activating protein catalytic alpha subunit 1
Synonyms gene GARNL1
Synonyms gene name GTPase activating RANGAP domain-like 1 GTPase activating Rap/RanGAP domain-like 1
Synonyms name tuberin-like protein 1 GAP-related interacting protein to E12
Locus 14q13, 2
Discovery year 2003-10-09
GenBank acession AK126975
Entrez gene record 253959
Pubmed identfication 19520869
RefSeq identity XM_210022
Havana BLAST/BLAT OTTHUMG00000170619

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