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GAS2 Antibody

GAS2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGAS2 Primary Polyclonal Antibody
Also known asGAS2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGAS2
SpecificityThis is a highly specific antibody against GAS2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GAS2
Gene ID number2620
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen During the G0-G1 transition phase Gas2 can be found phosphorylated on its serine residues, Gas2, Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts, Gas2 is believed to also be involved in the membrane ruffling process, Gas2 is mainly membrane-associated but when hyperphosphorylated it will accumulate at membrane ruffles, Gas2 is specifically expressed at growth arrest and is ubiquitously expressed with highest levels found in liver, Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases, The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells, There is no evidence, a component of the microfilament system, however, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis, lung and kidney, of Gas2 expression in spleen, Gas2 is a 313 amino acid protein encoded by the human gene GAS2
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GAS-2, GAS2_HUMAN, Gas2, Growth arrest specic 2, Growth arrest specic protein 2, Growth arrest-specic protein 2, MGC32610, GAS 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGAS2
Short nameGAS2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namegrowth arrest-specific 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target GAS2 and IDBG-36228 and ENSG00000148935 and 2620, GAS2 and IDBG-642237 and ENSBTAG00000021654 and 614840, Gas2 and IDBG-188499 and ENSMUSG00000030498 and 14453, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005884 and actin filament and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0016020 and membrane and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding, growth arrest-specific 2
Identity 4167
Gene GAS2
Long gene name growth arrest specific 2
Locus 11p14, 3
Discovery year 1997-08-28
GenBank acession BC040470
Entrez gene record 2620
Pubmed identfication 9521882
RefSeq identity NM_177553
Havana BLAST/BLAT OTTHUMG00000166071

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