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GAS2 Antibody, ALEXA FLUOR 488

GAS2 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, GAS2 Polyclonal Antibody
Also known asAnti-GAS2 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGAS2
SpecificityThis is a highly specific antibody against GAS2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GAS2
Gene ID Number2620
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen During the G0-G1 transition phase Gas2 can be found phosphorylated on its serine residues, Gas2, Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts, Gas2 is believed to also be involved in the membrane ruffling process, Gas2 is mainly membrane-associated but when hyperphosphorylated it will accumulate at membrane ruffles, Gas2 is specifically expressed at growth arrest and is ubiquitously expressed with highest levels found in liver, Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases, The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells, There is no evidence, a component of the microfilament system, however, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis, lung and kidney, of Gas2 expression in spleen, Gas2 is a 313 amino acid protein encoded by the human gene GAS2
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the GAS2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetGAS2
Short nameGAS2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, growth arrest-specific 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target GAS2 and IDBG-36228 and ENSG00000148935 and 2620, GAS2 and IDBG-642237 and ENSBTAG00000021654 and 614840, Gas2 and IDBG-188499 and ENSMUSG00000030498 and 14453, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005884 and actin filament and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0016020 and membrane and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding, growth arrest-specific 2
Identity 4167
Gene GAS2
Long gene name growth arrest specific 2
Locus 11p14, 3
Discovery year 1997-08-28
GenBank acession BC040470
Entrez gene record 2620
Pubmed identfication 9521882
RefSeq identity NM_177553
Havana BLAST/BLAT OTTHUMG00000166071

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