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GATA3 (Ser162) Antibody

GATA3 (Ser162) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGATA3 (Ser162) Primary Polyclonal Antibody
Also known asGATA3 (Ser162) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGATA3 Ser162
SpecificityThis is a highly specific antibody against GATA3 Ser162
Modification(s)Phosphorylation
Modification site(s)Ser162
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular location Helical, Extracellular
SourceKLH conjugated synthetic phosphopeptide derived from human GATA3 around the phosphorylation site of Ser162
Gene ID number2625
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen AGATCTTA, Although expression patterns of the various GATA transcription factors may overlap, Both GATA-4 and GATA-6 are found in heart, GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes, GATA-2 is expressed in embryonic brain and liver, GATA-3 is highly expressed in T lymphocytes, GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors, GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart, HeLa and endothelial cells, It is an essential component in the generation of the erythroid lineage, Studies with a modified GATA consensus sequence, This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1, as well as in erythroid cells, but not GATA-4 expression, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites, lung and liver tissues exhibit GATA-6, pancreas and ovary, Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GATA 3, GATA binding factor 3, GATA binding protein 3, GATA-3, GATA-binding factor 3, GATA3, GATA3 phospho Ser162, GATA3_HUMAN, HDR, MGC2346, MGC5199, MGC5445, Trans acting T cell specic transcription factor GATA 3, Trans-acting T-cell-specic transcription factor GATA-3, p-GATA3 Ser162, p-GATA3 phospho S162, GATA3 phospho S162
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGATA3 (Ser162)
Short nameGATA3 (Ser162) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGATA3 (Ser162) (Antibody to)
Alternative techniqueantibodies
Identity 4172
Gene GATA3
Long gene name GATA binding protein 3
Synonyms gene name GATA-binding protein 3
Synonyms HDR
Locus 10p14
Discovery year 1992-11-03
GenBank acession X55122
Entrez gene record 2625
Pubmed identfication 2050118 15087456
RefSeq identity NM_001002295
Classification GATA zinc finger domain containing
Havana BLAST/BLAT OTTHUMG00000017640

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