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GATA4 (Ser105) Antibody

GATA4 (Ser105) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGATA4 (Ser105) Primary Polyclonal Antibody
Also known asGATA4 (Ser105) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGATA4 Ser105
SpecificityThis is a highly specific antibody against GATA4 Ser105
Modification(s)Phosphorylation
Modification site(s)Ser105
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human GATA4 around the phosphorylation site of Ser105
Gene ID number2626
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen AGATCTTA, Although expression patterns of the various GATA transcription factors may overlap, Both GATA-4 and GATA-6 are found in heart, GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes, GATA-2 is expressed in embryonic brain and liver, GATA-3 is highly expressed in T lymphocytes, GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors, GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart, HeLa and endothelial cells, It is an essential component in the generation of the erythroid lineage, Studies with a modified GATA consensus sequence, This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1, as well as in erythroid cells, but not GATA-4 expression, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites, lung and liver tissues exhibit GATA-6, pancreas and ovary, Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GATA 4, GATA binding factor 4, GATA-4, GATA-binding factor 4, GATA-binding factor 4, GATA4, GATA4_HUMAN, Gata4, Transcription factor GATA-4, p-GATA-4Ser 105, p-GATA-4Ser105, GATA4 phospho S105
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGATA4 (Ser105)
Short nameGATA4 (Ser105) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGATA4 (Ser105) (Antibody to)
Alternative techniqueantibodies
Identity 4173
Gene GATA4
Long gene name GATA binding protein 4
Synonyms gene name GATA-binding protein 4
Locus 8p23, 1
Discovery year 1994-11-30
GenBank acession AK097060
Entrez gene record 2626
Pubmed identfication 7665171
RefSeq identity NM_002052
Classification GATA zinc finger domain containing
Havana BLAST/BLAT OTTHUMG00000090800

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