Name : GCAP1 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6613585302
| Long name | Biotin Conjugated, GCAP1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GCAP1 |
| Specificity | This is a highly specific antibody against GCAP1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human GCAP1 |
| Gene ID number | 2978 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | A related protein, By molecular cloning of human and mouse GCAP cDNA, GCAP1 is a calcium-binding protein that stimulates synthesis of c-GMP in photoreceptors, GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs, GCAP2, GCAPs are calcium-The binding proteins belonging to the calmodulin superfamily, In contrast to other calcium-binding proteins from the calmodulin superfamily, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, and containing three identically conserved calcium-binding sites, consisting of 201 to 205 amino acids, is detectable only in the retina and results from a gene duplication event, is mediated by guanylate cyclase-activating protein (GCAP1), the calcium-free form of GCAP1 stimulates the effector enzyme, the known mammalian GCAPs are found to be more than 90% similar, intracellular stimulation of guanylate cyclase (GC) by calcium |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | GCAP GCAP1 COD3 dJ139D8, 6 CORD14 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GCAP1 Conjugated |
| Short name | Conjugated, GCAP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, GCAP1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4678 |
| Gene | GUCA1A |
| Long gene name | guanylate cyclase activator 1A |
| Synonyms gene | GUCA GUCA1 C6orf131 |
| Synonyms gene name | chromosome 6 open reading frame 131 guanylate cyclase activator 1A (retina) |
| Synonyms name | cone dystrophy 3 |
| Locus | 6p21, 1 |
| Discovery year | 1992-04-08 |
| Entrez gene record | 2978 |
| Pubmed identfication | 9425234 |
| Classification | EF-hand domain containing |
| Havana BLAST/BLAT | OTTHUMG00000014696 |