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GCAP1 Antibody, Biotin Conjugated

GCAP1 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, GCAP1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGCAP1
SpecificityThis is a highly specific antibody against GCAP1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GCAP1
Gene ID number2978
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A related protein, By molecular cloning of human and mouse GCAP cDNA, GCAP1 is a calcium-binding protein that stimulates synthesis of c-GMP in photoreceptors, GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs, GCAP2, GCAPs are calcium-The binding proteins belonging to the calmodulin superfamily, In contrast to other calcium-binding proteins from the calmodulin superfamily, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, and containing three identically conserved calcium-binding sites, consisting of 201 to 205 amino acids, is detectable only in the retina and results from a gene duplication event, is mediated by guanylate cyclase-activating protein (GCAP1), the calcium-free form of GCAP1 stimulates the effector enzyme, the known mammalian GCAPs are found to be more than 90% similar, intracellular stimulation of guanylate cyclase (GC) by calcium
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms GCAP GCAP1 COD3 dJ139D8, 6 CORD14
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGCAP1 Conjugated
Short name Conjugated, GCAP1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, GCAP1 (Antibody to)
Alternative techniqueantibodies
Identity 4678
Gene GUCA1A
Long gene name guanylate cyclase activator 1A
Synonyms gene GUCA GUCA1 C6orf131
Synonyms gene name chromosome 6 open reading frame 131 guanylate cyclase activator 1A (retina)
Synonyms name cone dystrophy 3
Locus 6p21, 1
Discovery year 1992-04-08
Entrez gene record 2978
Pubmed identfication 9425234
Classification EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000014696

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