Name : GCAP2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2055386695
| Long name | GCAP2 Primary Polyclonal Antibody |
| Also known as | GCAP2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GCAP2 |
| Specificity | This is a highly specific antibody against GCAP2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GCAP2 |
| Gene ID number | 2979 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | A related protein, By molecular cloning of human and mouse GCAP cDNA, GCAP1 is a calcium-binding protein that stimulates synthesis of cGMP in photoreceptors, GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs, GCAP2, GCAPs are calcium-binding proteins belonging to the calmodulin superfamily, In contrast to other calcium-binding proteins from the calmodulin superfamily, The genes which encode GCAP1 and GCAP2 map to human chromosome 6p21, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, consisting of 201 to 205 amino acids and containing three identically conserved calcium-binding sites, is detectable only in the retina and results from a gene duplication event, is mediated by guanylate cyclase-activating protein (GCAP1), the calcium-free form of GCAP1 stimulates the effector enzyme, the known mammalian GCAPs are found to be more than 90% similar, 1, The intracellular stimulation of guanylate cyclase (GC) by calcium |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | GUC1B_HUMAN, GUCA 2, GUCA1B, Guanylate Cyclase Activating Protein Photoreceptor 2, Guanylate Cyclase Activator 1B, Guanylin 2, Guanylyl cyclase-activating protein 2, GCAP 2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GCAP2 |
| Short name | GCAP2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GCAP2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4679 |
| Gene | GUCA1B |
| Long gene name | guanylate cyclase activator 1B |
| Synonyms gene name | guanylate cyclase activator 1B (retina) |
| Synonyms | GCAP2 RP48 |
| Locus | 6p21, 1 |
| Discovery year | 1996-12-18 |
| GenBank acession | AF173227 |
| Entrez gene record | 2979 |
| Pubmed identfication | 9119368 |
| RefSeq identity | NM_002098 |
| Classification | EF-hand domain containing |
| Havana BLAST/BLAT | OTTHUMG00000014697 |