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GCAP3 Antibody, Biotin Conjugated

GCAP3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, GCAP3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGCAP3
SpecificityThis is a highly specific antibody against GCAP3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GCAP3
Gene ID number9626
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activation of GCAP3 leads to stimulation of guanylate cyclase 1 and 2 (GC1 and GC2), Calcium sensitive regulation of GC is essential in recovery of the rod receptor dark state following light exposure, GCAP3 (Guanylyl cyclase-activating protein 3), GCAPs are calcium-binding proteins belonging to the calmodulin superfamily and are specifically expressed in retina, There are two isoforms of GCAP3 that are produced as a result of alternative splicing events, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, also known as GUCA1C (Guanylate cyclase activator 1C), is a 209 amino acid EF-hand calcium binding protein that is activated by the decrease in calcium from the absorption of light by rhodopsin, is mediated by guanylate cyclase-activating proteins (GCAP), which increases cGMP concentration, The intracellular stimulation of guanylate cyclase (GC) by calcium
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms GCAP3
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGCAP3 Conjugated
Short name Conjugated, GCAP3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, GCAP3 (Antibody to)
Alternative techniqueantibodies
Identity 4680
Gene GUCA1C
Long gene name guanylate cyclase activator 1C
Synonyms name guanylyl cyclase-activating protein 3
Locus 3q13, 13
Discovery year 1999-03-12
GenBank acession AF110002
Entrez gene record 9626
Pubmed identfication 10037746 11860507
RefSeq identity NM_005459
Classification EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000159204

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