Name : GCAP3 Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN7836909235
| Long name | Cy7 Conjugated, GCAP3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GCAP3 |
| Specificity | This is a highly specific antibody against GCAP3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human GCAP3 |
| Gene ID number | 9626 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Activation of GCAP3 leads to stimulation of guanylate cyclase 1 and 2 (GC1 and GC2), Calcium sensitive regulation of GC is essential in recovery of the rod receptor dark state following light exposure, GCAP3 (Guanylyl cyclase-activating protein 3), GCAPs are calcium-binding proteins belonging to the calmodulin superfamily and are specifically expressed in retina, There are two isoforms of GCAP3 that are produced as a result of alternative splicing events, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, also known as GUCA1C (Guanylate cyclase activator 1C), is a 209 amino acid EF-hand calcium binding protein that is activated by the decrease in calcium from the absorption of light by rhodopsin, is mediated by guanylate cyclase-activating proteins (GCAP), which increases cGMP concentration, The intracellular stimulation of guanylate cyclase (GC) by calcium |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | GCAP3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | GCAP3 Conjugated |
| Short name | Conjugated, GCAP3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, GCAP3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4680 |
| Gene | GUCA1C |
| Long gene name | guanylate cyclase activator 1C |
| Synonyms name | guanylyl cyclase-activating protein 3 |
| Locus | 3q13, 13 |
| Discovery year | 1999-03-12 |
| GenBank acession | AF110002 |
| Entrez gene record | 9626 |
| Pubmed identfication | 10037746 11860507 |
| RefSeq identity | NM_005459 |
| Classification | EF-hand domain containing |
| Havana BLAST/BLAT | OTTHUMG00000159204 |