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GCN5 Antibody / KAT2A

GCN5 Antibody / KAT2A size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenGCN5 / KAT2A
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions1-0, 5ug/ml, Western blot: 0
NotesOptimal dilution of the GCN5 antibody should be determined by the researcher
Intented useThis GCN5 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q92830
PurityAntigen affinity
Description GCN4 and the HAP2-HAP3-HAP4 complex, GCN5 also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner, It is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator, The GCN4 protein activates transcription of a large number of amino acid biosynthetic genes under limiting amino acid conditions and the HAP2-HAP3-HAP4 complex is thought to mediate transcription of genes involved in respiratory functions, The GCN5 protein, a regulator of transcription activation in yeast, also called GCN5 and GCN5L2, is an enzyme that in humans is encoded by the KAT2A gene, promotes maximal levels of transcription by 2 transcriptional activators, Histone acetyltransferase KAT2A
ImmunogenAmino acids DPARPGLSQQQRASQRKAQVRGLPRAKKLEKL of human KAT2A/GCN5 were used as the immunogen for the GCN5 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the GCN5 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetGCN5 / KAT2A
Short nameGCN5 Antibody / KAT2A
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGCN5 (Antibody to) / K(lysine) acetyltransferase 2A
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007399 and nervous system development and biological process this GO :0008080 and N-acetyltransferase activity and molecular function this GO :0008152 and metabolic process and biological process this GO :0008283 and cell proliferation and biological process this GO :0010484 and H3 histone acetyltransferase activity and molecular function this GO :0016032 and viral process and biological process this GO :0016573 and histone acetylation and biological process this GO :0016578 and histone deubiquitination and biological process this GO :0021537 and telencephalon development and biological process this GO :0022037 and metencephalon development and biological process this GO :0030901 and midbrain development and biological process this GO :0030914 and STAGA complex and cellular component this GO :0031647 and regulation of protein stability and biological process this GO :0033276 and transcription factor TFTC complex and cellular component this GO :0035264 and multicellular organism growth and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0043966 and histone H3 acetylation and biological process this GO :0043983 and histone H4-K12 acetylation and biological process this GO :0043997 and histone acetyltransferase activity (H4-K12 specific) and molecular function this GO :0044154 and histone H3-K14 acetylation and biological process this GO :0045722 and positive regulation of gluconeogenesis and biological process this GO :0072686 and mitotic spindle and cellular component, GCN5 and GCN5L2 and hGCN5 and PCAF-b, KAT2A and IDBG-50287 and ENSG00000108773 and 2648, KAT2A and IDBG-640143 and ENSBTAG00000044019 and 514420, Kat2a and IDBG-211539 and ENSMUSG00000020918 and 14534, histone acetyltransferase activity (H4-K12 specific), nuclei, this GO :0000123 and histone acetyltransferase complex and cellular component this GO :0001701 and in utero embryonic development and biological process this GO :0001756 and somitogenesis and biological process this GO :0001843 and neural tube closure and biological process this GO :0003682 and chromatin binding and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0004402 and histone acetyltransferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005671 and Ada2/Gcn5/Ada3 transcription activator complex and cellular component this GO :0006325 and chromatin organization and biological process this GO :0006338 and chromatin remodeling and biological process this GO :0006355 and regulation of transcription, this GO :0003682: chromatin binding, this GO :0003682: chromatin binding and also this GO :0003713: transcription coactivator activity and also this GO :0004402: histone acetyltransferase activity and also this GO :0005515: protein binding and also this GO :0008080: N-acetyltransferase activity and also this GO :0010484: H3 histone acetyltransferase activity and also this GO :0042826: histone deacetylase binding and also this GO :0043997: histone acetyltransferase activity (H4-K12 specific), this GO :0003713: transcription coactivator activity, this GO :0004402: histone acetyltransferase activity, this GO :0005515: protein binding, this GO :0008080: N-acetyltransferase activity, this GO :0010484: H3 histone acetyltransferase activity, this GO :0042826: histone deacetylase binding, this GO :0043997: histone acetyltransferase activity (H4-K12 specific), K(lysine) acetyltransferase 2A
Identity 4201
Gene KAT2A
Long gene name lysine acetyltransferase 2A
Synonyms gene GCN5L2
Synonyms gene name GCN5 general control of amino-acid synthesis 5-like 2 (yeast) K(lysine) acetyltransferase 2A
Synonyms GCN5 PCAF-b
Locus 17q21, 2
Discovery year 1996-12-17
GenBank acession AF029777
Entrez gene record 2648
Pubmed identfication 8552087
RefSeq identity NM_021078
Classification Lysine acetyltransferases GCN5 related N-acetyltransferases ATAC complex SAGA complex
Havana BLAST/BLAT OTTHUMG00000133504

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