Name : GCOM1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6670341216
| Long name | GCOM1 Primary Polyclonal Antibody |
| Also known as | GCOM1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GCOM1 |
| Specificity | This is a highly specific antibody against GCOM1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GCOM1 |
| Gene ID number | 145781 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | CREB function and gene regulation, Gcom1 (GRINL1A complex locus protein 1), Gcom1 is expressed in small intestine, Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events, also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), both of which contain glutamate-gated, cation-specific ion channels, heart, is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, liver, lung, neural development and neurodegeneration, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor, Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | GRINL1A, GRINL1A combined protein, GRINL1A combined protein Gcom12, GRINL1A upstream protein, Glutamate receptor ionotropic N methyl D aspartate like 1A combined, Gup1, Gup2, NMDAR1 subunit interacting protein, Gcom2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GCOM1 |
| Short name | GCOM1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GCOM1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 26424 |
| Gene | GCOM1 |
| Long gene name | GRINL1A complex locus 1 |
| Synonyms | FLJ30973 GRINL1A MYZAP-POLR2M |
| Synonyms name | MYZAP-POLR2M readthrough |
| Locus | 15q21, 3 |
| Discovery year | 2008-08-05 |
| Entrez gene record | 145781 |
| Pubmed identfication | 15233991 18849881 |
| RefSeq identity | NM_001018090 |
| Havana BLAST/BLAT | OTTHUMG00000176411 |