Name : GCOM1 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN2514101251
| Long name | FITC Conjugated, GCOM1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GCOM1 |
| Specificity | This is a highly specific antibody against GCOM1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human GCOM1 |
| Gene ID number | 145781 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | CREB function and gene regulation, Gcom1 (GRINL1A complex locus protein 1), Gcom1 is expressed in small intestine, Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events, also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), both of which contain glutamate-gated, cation-specific ion channels, heart, is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, liver, lung, neural development and neurodegeneration, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor, Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | FLJ30973 GRINL1A MYZAP-POLR2M |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GCOM1 Conjugated |
| Short name | FITC Conjugated, GCOM1 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, GCOM1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 26424 |
| Gene | GCOM1 |
| Long gene name | GRINL1A complex locus 1 |
| Synonyms name | MYZAP-POLR2M readthrough |
| Locus | 15q21, 3 |
| Discovery year | 2008-08-05 |
| Entrez gene record | 145781 |
| Pubmed identfication | 15233991 18849881 |
| RefSeq identity | NM_001018090 |
| Havana BLAST/BLAT | OTTHUMG00000176411 |