GCS1 Antibody, Biotin Conjugated

GCS1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, GCS1 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	GCS1
Specificity	This is a highly specific antibody against GCS1
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human GCS1
Gene ID number	7841
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Glucosidase I catalyzes the first step in the N-linked oligosaccharide processing pathway, Glucosidase I contains a short cytosolic tail, It specifically removes the distal alpha 1, Mutations in the gene encoding Glucosidase I result in the congenital disorder glycosylation (CDG-IIb), Two point mutations in the Glucosidase I gene have been identified and result in amino acid substitutions, a single pass transmembrane domain and a large C-terminal catalytic domain located on the luminal side of the ER, dysmorphic features, feeding problems, hepatomegaly, hypoventilation, namely Arg486Thr and Phe652Leu, seizures and death, that affect polypeptide folding and active site formation, which is characterized by generalized hypotonia, 2-linked glucose residue from the Glc3-Man9-GlcNAc2 oligosaccharide precursor, Glycosylation of asparagine residues in Asn-X-Ser/Thr motifs in proteins commonly occur in the lumen of the endoplasmic reticulum (ER)
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	GCS1 CWH41 DER7
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	GCS1 Conjugated
Short name	Conjugated, GCS1 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, GCS1 (Antibody to)
Alternative technique	antibodies
Identity	24862
Gene	MOGS
Long gene name	mannosyl-oligosaccharide glucosidase
Synonyms name	glucosidase I processing A-glucosidase I
Locus	2p13, 1
Discovery year	2009-03-24
GenBank acession	X87237
Entrez gene record	7841
Pubmed identfication	7635146 8786151
RefSeq identity	NM_006302
Havana BLAST/BLAT	OTTHUMG00000152886

GCS1 Antibody, Biotin Conjugated

GCS1 Antibody, Biotin Conjugated size: 0.1ml 333

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