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GDAP1 Antibody

GDAP1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGDAP1 Primary Polyclonal Antibody
Also known asGDAP1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGDAP1
SpecificityThis is a highly specific antibody against GDAP1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GDAP1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Although it shares the carboxy and amino-terminal glutathione S-transferase domains, GDAP1 is characterized as a GST-like protein because it contains an extended GST domain II and a predicted transmembrane domain, GDAP1 may function in a signal transduction pathway that is responsible for ganglioside-induced neurite differentiation and also may play a role in protecting myelin membranes from free-radical damage, Mutations in the gene encoding GDAP1 is the cause of many forms of Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system that is characterized by reduced nerve conduction velocities, slow progressive distal muscle atrophy and absent deep tendon reflexes, two characteristics which are unusual for GST family members, Glutathione S-transferases (GSTs) function to conjugate reduced glutathione to many exogenous and endogenous hydrophobic electrophiles
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GDAP1, GDAP1_HUMAN, Ganglioside-induced dferentiation-associated protein 1, Ganglioside induced dferentiation associated protein 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGDAP1
Short nameGDAP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGDAP1 (Antibody to)
Alternative techniqueantibodies
Identity 15968
Gene GDAP1
Long gene name ganglioside induced differentiation associated protein 1
Synonyms gene CMT4A
Synonyms gene name Charcot-Marie-Tooth neuropathy 4A
Synonyms CMT4 CMT2K
Locus 8q21, 11
Discovery year 2001-06-25
Entrez gene record 54332
Pubmed identfication 8268915 11743579
RefSeq identity NM_018972
Havana BLAST/BLAT OTTHUMG00000164509
Locus Specific Databases Inherited Peripheral Neuropathies Mutation Database LRG_244

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