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GDF6 Antibody

GDF6 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGDF6 Primary Polyclonal Antibody
Also known asGDF6 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGDF6
SpecificityThis is a highly specific antibody against GDF6
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GDF6
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen (5), GDF-1 expression is almost exclusively restricted to the central nervous system and mediates cell differentiation events during embryonic development (3), GDF-3 is detectable in bone marrow, GDF-5 (also designated CDMP-1) has been shown to induce activation of plasminogen activator, GDF-5 mutations have been identified in mice with the mutation brachypodism (bp), GDF-6 and GDF-7 are closely related to GDF-5 (6), GDF-8 has been shown to be a negative regulator of skeletal muscle mass (1), It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation, Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis (1), Neither GDF-3 (Vgr-2) nor GDF-9 contains the conserved cysteine residue which is found in most other TGF superfamily members, a mutation which affects the length and number of bones in limbs (6), spleen, thereby inducing angiogenesis, thymus and adipose tissue, whereas GDF-9 has only been detected in ovary (4), 2), Growth/differentiation factors (GDFs) are members of the TGF superfamily (1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CDMP2, Cartilage Derived Morphogenetic Protein 2, GDF16 , GDF6_HUMAN, Growth dferentiation factor 6, Growth/dferentiation factor 6, bmp-13, bmp13, cdmp 2, gdf 6, bmp 13
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGDF6
Short nameGDF6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namegrowth differentiation factor 6 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, DNA-templated and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :1990009 and retinal cell apoptotic process and biological process, Extracellular, GDF6 and IDBG-29375 and ENSG00000156466 and 392255, Gdf6 and IDBG-129105 and ENSMUSG00000051279 and 242316, protein homodimerization activity, this GO :0005125 and cytokine activity and molecular function this GO :0005615 and extracellular space and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008083 and growth factor activity and molecular function this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0032924 and activin receptor signaling pathway and biological process this GO :0040007 and growth and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045893 and positive regulation of transcription, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0008083: growth factor activity and also this GO :0042803: protein homodimerization activity, this GO :0008083: growth factor activity, this GO :0042803: protein homodimerization activity, 29849 and IDBG-645217 and ENSBTAG00000007687 and 407175, growth differentiation factor 6
Identity 4221
Gene GDF6
Long gene name growth differentiation factor 6
Synonyms gene SGM1
Synonyms gene name segmentation syndrome 1
Synonyms BMP13 KFS KFS1
Locus 8q22, 1
Discovery year 1999-04-23
Entrez gene record 392255
Pubmed identfication 10022976 18425797
RefSeq identity NM_001001557
Havana BLAST/BLAT OTTHUMG00000164710

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