| Long name | GDF7 Primary Polyclonal Antibody |
| Also known as | GDF7 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GDF7 |
| Specificity | This is a highly specific antibody against GDF7 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GDF7 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | (5), GDF-1 expression is almost exclusively restricted to the central nervous system and mediates cell differentiation events during embryonic development (3), GDF-3 is detectable in bone marrow, GDF-5 (also designated CDMP-1) has been shown to induce activation of plasminogen activator, GDF-5 mutations have been identified in mice with the mutation brachypodism (bp), GDF-6 and GDF-7 are closely related to GDF-5 (6), GDF-8 has been shown to be a negative regulator of skeletal muscle mass (1), It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation, Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis (1), Neither GDF-3 (Vgr-2) nor GDF-9 contains the conserved cysteine residue which is found in most other TGF superfamily members, a mutation which affects the length and number of bones in limbs (6), spleen, thereby inducing angiogenesis, thymus and adipose tissue, whereas GDF-9 has only been detected in ovary (4), 2), Growth/differentiation factors (GDFs) are members of the TGF superfamily (1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | GDF-7, GDF7_HUMAN, Gdf 7, Growth/dferentiation factor 7, bone morphogenetic protein 12, growth dferentiation factor 7, bmp12 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GDF7 |
| Short name | GDF7 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | growth differentiation factor 7 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0048608 and reproductive structure development and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0048853 and forebrain morphogenesis and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :0060571 and morphogenesis of an epithelial fold and biological process this GO :2001051 and positive regulation of tendon cell differentiation and biological process, Extracellular, GDF7 and IDBG-32594 and ENSG00000143869 and 151449, GDF7 and IDBG-637592 and ENSBTAG00000038224 and 286859, Gdf7 and IDBG-128342 and ENSMUSG00000037660 and 238057, protein homodimerization activity, this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007411 and axon guidance and biological process this GO :0008083 and growth factor activity and molecular function this GO :0010628 and positive regulation of gene expression and biological process this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0021509 and roof plate formation and biological process this GO :0021527 and spinal cord association neuron differentiation and biological process this GO :0021915 and neural tube development and biological process this GO :0022612 and gland morphogenesis and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030855 and epithelial cell differentiation and biological process this GO :0030901 and midbrain development and biological process this GO :0032924 and activin receptor signaling pathway and biological process this GO :0040007 and growth and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045165 and cell fate commitment and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045893 and positive regulation of transcription, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity and also this GO :0042803: protein homodimerization activity, this GO :0005515: protein binding, this GO :0008083: growth factor activity, this GO :0042803: protein homodimerization activity, growth differentiation factor 7 |
| Identity | 4222 |
| Gene | GDF7 |
| Long gene name | growth differentiation factor 7 |
| Synonyms | BMP12 |
| Locus | 2p24, 1 |
| Discovery year | 1999-04-23 |
| GenBank acession | AF522369 |
| Entrez gene record | 151449 |
| Pubmed identfication | 10022976 9808626 |
| RefSeq identity | NM_182828 |
| Havana BLAST/BLAT | OTTHUMG00000090781 |
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