Name : GDF8/MSTN Antibody, Cy5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN1920279385
| Long name | Cy5 Conjugated, GDF8/MSTN Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GDF8/MSTN |
| Specificity | This is a highly specific antibody against GDF8/MSTN |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 300-350/375 |
| Source | KLH conjugated synthetic peptide derived from human GDF8 |
| Gene ID number | 2660 |
| Swiss Prot | O14793 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Acts specifically as a negative regulator of skeletal muscle growth, Belongs to the TGF-beta family, The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues, This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth, This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues, Weak expression in adipose tissue, [SUBUNIT] Homodimer, [TISSUE SPECIFICITY] Expressed specifically in developing and adult skeletal muscle, The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 625, 650nm/670nm |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GDF8/MSTN Conjugated |
| Short name | Conjugated, GDF8/MSTN Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy5 |
| Alternative name | cyanine 5 coupled, GDF8/myostatin (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0048632 and negative regulation of skeletal muscle tissue growth and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051602 and response to electrical stimulus and biological process this GO :0071549 and cellular response to dexamethasone stimulus and biological process, Extracellular, GDF8 and MSLHP, MSTN and IDBG-639462 and ENSBTAG00000011808 and 281187, MSTN and IDBG-77438 and ENSG00000138379 and 2660, Mstn and IDBG-153903 and ENSMUSG00000026100 and 17700, identical protein binding, this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007517 and muscle organ development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0009408 and response to heat and biological process this GO :0009629 and response to gravity and biological process this GO :0014732 and skeletal muscle atrophy and biological process this GO :0014741 and negative regulation of muscle hypertrophy and biological process this GO :0014850 and response to muscle activity and biological process this GO :0022602 and ovulation cycle process and biological process this GO :0033574 and response to testosterone and biological process this GO :0040007 and growth and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043403 and skeletal muscle tissue regeneration and biological process this GO :0043627 and response to estrogen and biological process this GO :0045471 and response to ethanol and biological process this GO :0045893 and positive regulation of transcription, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005125: cytokine activity and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity and also this GO :0008201: heparin binding and also this GO :0042802: identical protein binding, this GO :0005125: cytokine activity, this GO :0005515: protein binding, this GO :0008083: growth factor activity, this GO :0008201: heparin binding, this GO :0042802: identical protein binding, myostatin |
| Identity | 4223 |
| Gene | MSTN |
| Long gene name | myostatin |
| Synonyms gene | GDF8 |
| Synonyms gene name | growth differentiation factor 8 |
| Locus | 2q32, 2 |
| Discovery year | 1997-09-12 |
| GenBank acession | AF019627 |
| Entrez gene record | 2660 |
| Pubmed identfication | 9288100 10610713 17003236 |
| RefSeq identity | NM_005259 |
| Havana BLAST/BLAT | OTTHUMG00000132663 |
| Locus Specific Databases | Leiden Muscular Dystrophy pages LRG_200 |