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GEFT Antibody

GEFT Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGEFT Primary Polyclonal Antibody
Also known asGEFT PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGEFT
SpecificityThis is a highly specific antibody against GEFT
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GEFT
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain, GEFT is an important regulator of processes involved in axon and dendrite formation, GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers, GEFT seems to be an exchange factor primarily for Rac 1 in neurons, GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation, Involved in skeletal myogenesis, and weakly expressed in small intestine, colon, heart and muscle, liver, placenta and lung, GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ARHGP_HUMAN, GEFT, Guanine nucleotide exchange factor GEFT, RAC/CDC42 exchange factor, Rac/Cdc42/Rho exchange factor GEFT, Rho guanine nucleotide exchange factor 25, RhoA/RAC/CDC42 exchange factor, RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT, p63RhoGEF, p63RhoGEF , ARHGEF25
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGEFT
Short nameGEFT Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGEFT (Antibody to)
Alternative techniqueantibodies
Identity 30275
Gene ARHGEF25
Long gene name Rho guanine nucleotide exchange factor 25
Synonyms gene name Rho guanine nucleotide exchange factor (GEF) 25
Synonyms GEFT p63RhoGEF
Synonyms name RAC/CDC42 exchange factor
Locus 12q13, 3
Discovery year 2010-09-02
Entrez gene record 115557
Pubmed identfication 12547822
RefSeq identity NM_133483
Classification Rho guanine nucleotide exchange factors
Havana BLAST/BLAT OTTHUMG00000152516

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