Name : GEFT Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4725433265
| Long name | ALEXA FLUOR 488 Conjugated, GEFT Polyclonal Antibody |
| Also known as | Anti-GEFT PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GEFT |
| Specificity | This is a highly specific antibody against GEFT |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GEFT |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain, GEFT is an important regulator of processes involved in axon and dendrite formation, GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers, GEFT seems to be an exchange factor primarily for Rac 1 in neurons, GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation, Involved in skeletal myogenesis, and weakly expressed in small intestine, colon, heart and muscle, liver, placenta and lung, GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | GEFT p63RhoGEF |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the GEFT Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | GEFT |
| Short name | GEFT Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, GEFT (Antibody to) |
| Alternative technique | antibodies |
| Identity | 30275 |
| Gene | ARHGEF25 |
| Long gene name | Rho guanine nucleotide exchange factor 25 |
| Synonyms gene name | Rho guanine nucleotide exchange factor (GEF) 25 |
| Synonyms name | RAC/CDC42 exchange factor |
| Locus | 12q13, 3 |
| Discovery year | 2010-09-02 |
| Entrez gene record | 115557 |
| Pubmed identfication | 12547822 |
| RefSeq identity | NM_133483 |
| Classification | Rho guanine nucleotide exchange factors |
| Havana BLAST/BLAT | OTTHUMG00000152516 |