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GEFT Antibody, ALEXA FLUOR 488

GEFT Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, GEFT Polyclonal Antibody
Also known asAnti-GEFT PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGEFT
SpecificityThis is a highly specific antibody against GEFT
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GEFT
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain, GEFT is an important regulator of processes involved in axon and dendrite formation, GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers, GEFT seems to be an exchange factor primarily for Rac 1 in neurons, GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation, Involved in skeletal myogenesis, and weakly expressed in small intestine, colon, heart and muscle, liver, placenta and lung, GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms GEFT p63RhoGEF
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the GEFT Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetGEFT
Short nameGEFT Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, GEFT (Antibody to)
Alternative techniqueantibodies
Identity 30275
Gene ARHGEF25
Long gene name Rho guanine nucleotide exchange factor 25
Synonyms gene name Rho guanine nucleotide exchange factor (GEF) 25
Synonyms name RAC/CDC42 exchange factor
Locus 12q13, 3
Discovery year 2010-09-02
Entrez gene record 115557
Pubmed identfication 12547822
RefSeq identity NM_133483
Classification Rho guanine nucleotide exchange factors
Havana BLAST/BLAT OTTHUMG00000152516

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